Bopindolol

CARDIOVASCULAR SYSTEM

Key facts

Bopindolol is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1985. DrugCentral lists 8 molecular targets, including ADRB2, ADRB1 and HTR1A.

• Molecular targets: ADRB2, ADRB1, HTR1A and Htr1a (8 listed in DrugCentral).
• ATC code: C07AA17 (Beta blocking agents, non-selective).
• Molecular formula: C23H28N2O3; molecular weight 380.49 g/mol.

Mechanism & targets

Molecular targets (8)

Target	Gene	Action	Activity
Beta-2 adrenergic receptor	ADRB2	antagonist	Ki 9.65
Beta-1 adrenergic receptor	ADRB1	antagonist	Ki 9.51
5-hydroxytryptamine receptor 1A	HTR1A	unknown	Ki 6.82
5-hydroxytryptamine receptor 1A	Htr1a	unknown	IC50 6.57
Beta-3 adrenergic receptor	ADRB3	unknown	Ki 6.46
5-hydroxytryptamine receptor 2A	HTR2A	unknown	Ki 6.34
5-hydroxytryptamine receptor 2B	HTR2B	unknown	Ki 6.01
Cytochrome P450 2D6	CYP2D6	unknown	IC50 5.26

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1985-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
C07AA17	CARDIOVASCULAR SYSTEM › BETA BLOCKING AGENTS › BETA BLOCKING AGENTS › Beta blocking agents, non-selective
C07CA17	CARDIOVASCULAR SYSTEM › BETA BLOCKING AGENTS › BETA BLOCKING AGENTS AND OTHER DIURETICS › Beta blocking agents, non-selective, and other diuretics

Chemical structure

• Molecular formula: C₂₃H₂₈N₂O₃
• Molecular weight: 380.49 g/mol
• CAS number: 62658-63-3
• InChIKey: UUOJIACWOAYWEZ-UHFFFAOYSA-N
• PubChem CID: 44112

CC1=CC2=C(N1)C=CC=C2OCC(CNC(C)(C)C)OC(=O)C1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Bopindolol work?

Its molecular targets in DrugCentral include ADRB2 (antagonist), ADRB1 (antagonist), HTR1A and Htr1a.

When was Bopindolol first approved?

Bopindolol was first approved by the YEAR INTRODUCED in 1985.

What is the chemical formula of Bopindolol?

Bopindolol has the molecular formula C23H28N2O3 and a molecular weight of 380.49 g/mol.

Sources

• DrugCentral drug card 389 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1878625 — compound record and bioactivity
• PubChem CID 44112 — chemical identifiers
• DrugBank DB08807 — drug record
• FDA UNII KT304VZO57 — substance identity
• UniProt P07550 (ADRB2) — target protein
• UniProt P08588 (ADRB1) — target protein
• UniProt P08908 (HTR1A) — target protein
• UniProt P13945 (ADRB3) — target protein
• UniProt P28223 (HTR2A) — target protein
• UniProt P41595 (HTR2B) — target protein

How this page is built: methodology · editorial policy & corrections.