Indoramin

CARDIOVASCULAR SYSTEM

Key facts

Indoramin is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1981. DrugCentral lists 11 molecular targets, including ADRA1A, ADRA1A and DRD4.

• Molecular targets: ADRA1A, ADRA1A, DRD4 and Adra1b|Adra1d|Adra1a (11 listed in DrugCentral).
• ATC code: C02CA02 (Alpha-adrenoreceptor antagonists).
• Molecular formula: C22H25N3O; molecular weight 347.46 g/mol.

Mechanism & targets

Molecular targets (11)

Target	Gene	Action	Activity
Alpha-1A adrenergic receptor	ADRA1A	unknown	Ki 8.43
Alpha-1A adrenergic receptor	ADRA1A	unknown	Ki 7.92
D(4) dopamine receptor	DRD4	unknown	Ki 7.75
Adrenergic receptor alpha-1	Adra1b|Adra1d|Adra1a	unknown	Ki 7.61
Alpha-1B adrenergic receptor	ADRA1B	unknown	Ki 7.60
Alpha-1D adrenergic receptor	ADRA1D	unknown	Ki 6.96
Alpha-2C adrenergic receptor	ADRA2C	unknown	Ki 6.32
Alpha-2B adrenergic receptor	ADRA2B	unknown	Ki 6.28
Alpha-1D adrenergic receptor	Adra1d	unknown	Ki 6.21
Alpha-2A adrenergic receptor	ADRA2A	unknown	Ki 5.65
Adrenergic receptor alpha-2	Adra2b|Adra2c|Adra2a	unknown	Ki 4.92

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1981-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
C02CA02	CARDIOVASCULAR SYSTEM › ANTIHYPERTENSIVES › ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING › Alpha-adrenoreceptor antagonists

Chemical structure

• Molecular formula: C₂₂H₂₅N₃O
• Molecular weight: 347.46 g/mol
• CAS number: 26844-12-2
• InChIKey: JXZZEXZZKAWDSP-UHFFFAOYSA-N
• PubChem CID: 33625

O=C(NC1CCN(CCC2=CNC3=C2C=CC=C3)CC1)C1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Indoramin work?

Its molecular targets in DrugCentral include ADRA1A, ADRA1A, DRD4 and Adra1b|Adra1d|Adra1a.

When was Indoramin first approved?

Indoramin was first approved by the YEAR INTRODUCED in 1981.

What is the chemical formula of Indoramin?

Indoramin has the molecular formula C22H25N3O and a molecular weight of 347.46 g/mol.

Sources

• DrugCentral drug card 1443 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL279516 — compound record and bioactivity
• PubChem CID 33625 — chemical identifiers
• DrugBank DB08950 — drug record
• FDA UNII 0Z802HMY7H — substance identity
• UniProt P35348 (ADRA1A) — target protein
• UniProt P21917 (DRD4) — target protein
• UniProt P35368 (ADRA1B) — target protein
• UniProt P25100 (ADRA1D) — target protein
• UniProt P18825 (ADRA2C) — target protein
• UniProt P18089 (ADRA2B) — target protein

How this page is built: methodology · editorial policy & corrections.