Coumafos

Drug profile

Key facts

Coumafos is a drug catalogued in DrugCentral. DrugCentral lists 11 molecular targets, including CA6, CA5B and CA14.

• Molecular targets: CA6, CA5B, CA14 and CA13 (11 listed in DrugCentral).
• Molecular formula: C14H16ClO5PS; molecular weight 362.76 g/mol.

Mechanism & targets

Molecular targets (11)

Target	Gene	Action	Activity
Carbonic anhydrase 6	CA6	unknown	Ki 5.65
Carbonic anhydrase 5B, mitochondrial	CA5B	unknown	Ki 5.47
Carbonic anhydrase 14	CA14	unknown	Ki 5.38
Carbonic anhydrase 13	CA13	unknown	Ki 5.37
Carbonic anhydrase 3	CA3	unknown	Ki 5.33
Carbonic anhydrase 7	CA7	unknown	Ki 5.33
Carbonic anhydrase 5A, mitochondrial	CA5A	unknown	Ki 5.29
Carbonic anhydrase 4	CA4	unknown	Ki 5.26
Carbonic anhydrase 9	CA9	unknown	Ki 5.19
Carbonic anhydrase 12	CA12	unknown	Ki 5.02
Carbonic anhydrase 1	CA1	unknown	Ki 4.21

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Coumafos is on its molecule page.

• Molecular formula: C₁₄H₁₆ClO₅PS
• Molecular weight: 362.76 g/mol
• CAS number: 56-72-4
• InChIKey: BXNANOICGRISHX-UHFFFAOYSA-N
• PubChem CID: 2871

CCOP(=S)(OCC)OC1=CC=C2C(C)=C(Cl)C(=O)OC2=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Coumafos work?

Its molecular targets in DrugCentral include CA6, CA5B, CA14 and CA13.

What is the chemical formula of Coumafos?

Coumafos has the molecular formula C14H16ClO5PS and a molecular weight of 362.76 g/mol.

Sources

• DrugCentral drug card 5667 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL251680 — compound record and bioactivity
• PubChem CID 2871 — chemical identifiers
• DrugBank DB11390 — drug record
• FDA UNII L08SZ5Z5JC — substance identity
• DailyMed: FDA labels for Coumafos — current prescribing information (label search)
• UniProt P23280 (CA6) — target protein
• UniProt Q9Y2D0 (CA5B) — target protein
• UniProt Q9ULX7 (CA14) — target protein
• UniProt Q8N1Q1 (CA13) — target protein
• UniProt P07451 (CA3) — target protein
• UniProt P43166 (CA7) — target protein

How this page is built: methodology · editorial policy & corrections.