Laropiprant

Drug profile

Key facts

Laropiprant is a drug catalogued in DrugCentral. DrugCentral lists 10 molecular targets, including PTGDR, TBXA2R and PTGER2. Recorded indications include Dyslipidemia.

• Molecular targets: PTGDR, TBXA2R, PTGER2 and TSPO (10 listed in DrugCentral).
• Indications: Dyslipidemia.
• Molecular formula: C21H19ClFNO4S; molecular weight 435.90 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Dyslipidemia

Mechanism & targets

Molecular targets (10)

Target	Gene	Action	Activity
Prostaglandin D2 receptor	PTGDR	antagonist	Kd 10.52
Thromboxane A2 receptor	TBXA2R	unknown	Ki 8.53
Prostaglandin E2 receptor EP2 subtype	PTGER2	unknown	Ki 6.87
Translocator protein	TSPO	unknown	Ki 6.54
Prostaglandin D2 receptor 2	PTGDR2	unknown	Ki 6.13
Prostaglandin E2 receptor EP3 subtype	PTGER3	unknown	Ki 6.05
D(3) dopamine receptor	DRD3	unknown	Ki 5.95
Prostaglandin E2 receptor EP1 subtype	PTGER1	unknown	Ki 5.94
Prostacyclin receptor	PTGIR	unknown	Ki 5.18
Prostaglandin F2-alpha receptor	PTGFR	unknown	Ki 5.00

Chemical structure

• Molecular formula: C₂₁H₁₉ClFNO₄S
• Molecular weight: 435.90 g/mol
• CAS number: —
• InChIKey: NXFFJDQHYLNEJK-CYBMUJFWSA-N
• PubChem CID: 9867642

CS(=O)(=O)C1=C2N(CC3=CC=C(Cl)C=C3)C3=C(CC[C@@H]3CC(O)=O)C2=CC(F)=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Laropiprant used for?

DrugCentral lists the following indications for Laropiprant: Dyslipidemia.

How does Laropiprant work?

Its molecular targets in DrugCentral include PTGDR (antagonist), TBXA2R, PTGER2 and TSPO.

What is the chemical formula of Laropiprant?

Laropiprant has the molecular formula C21H19ClFNO4S and a molecular weight of 435.90 g/mol.

Sources

• DrugCentral drug card 4326 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL426559 — compound record and bioactivity
• PubChem CID 9867642 — chemical identifiers
• DrugBank DB11629 — drug record
• FDA UNII G7N11T8O78 — substance identity
• UniProt Q13258 (PTGDR) — target protein
• UniProt P21731 (TBXA2R) — target protein
• UniProt P43116 (PTGER2) — target protein
• UniProt P30536 (TSPO) — target protein
• UniProt Q9Y5Y4 (PTGDR2) — target protein
• UniProt P43115 (PTGER3) — target protein

How this page is built: methodology · editorial policy & corrections.