Enoxolone

DERMATOLOGICALS

Key facts

Enoxolone is a drug catalogued in DrugCentral. DrugCentral lists 18 molecular targets, including HSD11B2, Hsd11b1 and HSD11B1.

• Molecular targets: HSD11B2, Hsd11b1, HSD11B1 and Hsd11b1 (18 listed in DrugCentral).
• ATC code: D03AX10 (Other cicatrizants).
• Molecular formula: C30H46O4; molecular weight 470.69 g/mol.

Mechanism & targets

Molecular targets (18)

Target	Gene	Action	Activity
Corticosteroid 11-beta-dehydrogenase isozyme 2	HSD11B2	unknown	IC50 8.91
Corticosteroid 11-beta-dehydrogenase isozyme 1	Hsd11b1	unknown	IC50 8.70
Corticosteroid 11-beta-dehydrogenase isozyme 1	HSD11B1	unknown	IC50 8.07
Corticosteroid 11-beta-dehydrogenase isozyme 1	Hsd11b1	unknown	IC50 7.05
Protein kinase C eta type	PRKCH	unknown	Kd 6.60
Lactoylglutathione lyase	Glo1	unknown	Ki 6.54
Corticosteroid 11-beta-dehydrogenase isozyme 2	Hsd11b2	unknown	IC50 6.44
Aldo-keto reductase family 1 member B10	AKR1B10	unknown	IC50 5.31
Tyrosine-protein phosphatase non-receptor type 11	PTPN11	unknown	IC50 5.02
Beta-glucuronidase	uidA	unknown	IC50 4.92
Liver carboxylesterase 1	CES1	unknown	IC50 4.68
Arachidonate 5-lipoxygenase	ALOX5	unknown	IC50 4.61
Tyrosine-protein phosphatase non-receptor type 1	PTPN1	unknown	IC50 4.34
Protein-tyrosine phosphatase 1C	PTPN6	unknown	IC50 4.18
Glycogen phosphorylase, muscle form	PYGM	unknown	IC50 4.18
Cocaine esterase	CES2	unknown	IC50 4.16
High mobility group protein B1	HMGB1	unknown	Kd 4.06
Beta-glucuronidase	Gusb	unknown	IC50 4.01

ATC classification

ATC code	Therapeutic hierarchy
D03AX10	DERMATOLOGICALS › PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS › CICATRIZANTS › Other cicatrizants

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Enoxolone is on its molecule page.

• Molecular formula: C₃₀H₄₆O₄
• Molecular weight: 470.69 g/mol
• CAS number: 471-53-4
• InChIKey: MPDGHEJMBKOTSU-YKLVYJNSSA-N
• PubChem CID: 10114

CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Enoxolone work?

Its molecular targets in DrugCentral include HSD11B2, Hsd11b1, HSD11B1 and Hsd11b1.

What is the chemical formula of Enoxolone?

Enoxolone has the molecular formula C30H46O4 and a molecular weight of 470.69 g/mol.

Sources

• DrugCentral drug card 3178 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL230006 — compound record and bioactivity
• PubChem CID 10114 — chemical identifiers
• DrugBank DB13089 — drug record
• FDA UNII P540XA09DR — substance identity
• UniProt P80365 (HSD11B2) — target protein
• UniProt P28845 (HSD11B1) — target protein
• UniProt P24723 (PRKCH) — target protein
• UniProt O60218 (AKR1B10) — target protein
• UniProt Q06124 (PTPN11) — target protein
• UniProt P23141 (CES1) — target protein

How this page is built: methodology · editorial policy & corrections.